Varadarajan SG, Kong JH, Phan KD, Kao T-J, Panaitof SC, Cardin J, Eltzschig H, Kania A, Novitch BG, Butler SJ. Netrin1 produced by neural progenitors, not floor plate cells, is required for axon guidance in the spinal cord  Neuron. 2017 April 20; 94:1-10. [Abstract] [Article]
Mar 21; 46:1-11.
Huang C, Su T, Xue Y, Cheng C, Lay FD, McKee RA, Li M, Vashisht A, Wohlschlegel J, Novitch BG, Plath K, Kurdistani SK, Carey M. Genes Dev. 2017 Feb 1;31(3):241-246. [Abstract] [Article]
Linares AJ, Lin CH, Damianov A, Adams KL, Novitch BG, Black DL.  The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation. eLife. 2015 Dec 24;4. pii: e09268. doi:10.7554/eLife.09268. [Abstract] [Article]
Kong JH*, Yang L*, Dessaud E, Chuang K, Moore DM, Rohatgi R, Briscoe J, Novitch  BG. Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. Dev Cell. 2015 May 26;33(4):373-87. [Abstract] [Article] [Cover art] [Preview] [Science Signaling Editor's Choice]
Adams KL, Rousso DL, Umbach JA, Novitch BG. Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015 Apr 14;6:6778. [Abstract] [Article]
Pearson CA, Butler SJ, Novitch BG. Neuronal organization: unsticking the cadherin code. Curr Biol. 2014 Dec 1;24(23):R1127-9. [Abstract] [Article]
Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R. Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling. Cell Rep. 2014 Jan 16;6(1):168-81. [Abstract] [Article]
Xu B, Hrycaj SM, McIntyre DC, Baker NC, Takeuchi JK, Jeannotte L, Gaber ZB, Novitch BG, Wellik DM. Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19438-43. [Abstract] [Article]
Gaber ZB, Butler SJ, Novitch BG. PLZF regulates fibroblast growth factor responsiveness and maintenance of neural progenitors. PLoS Biol. 2013 Oct;11(10):e1001676. [Abstract] [Article] [Cover Art]
Kong JH, Butler SJ, Novitch BG. My brain told me to do it. Dev Cell. 2013 Jun  10;25(5):436-8. [Abstract] [Article]
Jacob J, Kong J, Moore S, Milton C, Sasai N, Gonzalez-Quevedo R, Terriente J,  Imayoshi I, Kageyama R, Wilkinson DG, Novitch BG, Briscoe J. Retinoid acid specifies neuronal identity through graded expression of Ascl1. Curr Biol. 2013 Mar 4;23(5):412-8. [Abstract] [Article]
Wang Y, Kim E, Wang X, Novitch BG, Yoshikawa K, Chang LS, Zhu Y. ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities. Cell. 2012 Aug 17;150(4):816-30. [Abstract] [Article]
Roy A, Francius C, Rousso DL, Seuntjens E, Debruyn J, Luxenhofer G, Huber AB, Huylebroeck D, Novitch BG, Clotman F. Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification. Development. 2012 Sep;139(17):3109-19. [Abstract] [Article]
Umbach JA, Adams KL, Gundersen CB, Novitch BG. Functional neuromuscular junctions formed by embryonic stem cell-derived motor neurons. PLoS One. 2012;7(5):e36049. [Abstract] [Article]
Rousso DL, Pearson CA, Gaber ZB, Miquelajauregui A, Li S, Portera-Cailliau C, Morrisey EE, Novitch BG. Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. Neuron. 2012 Apr 26;74(2):314-30. [Abstract] [Article] [Cover Art] [Preview]
Kang P, Lee HK, Glasgow SM, Finley M, Donti T, Gaber ZB, Graham BH, Foster AE, Novitch BG, Gronostajski RM, Deneen B. Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron.  2012 Apr 12;74(1):79-94. [Abstract] [Article]
Skaggs K, Martin DM, Novitch BG. Regulation of spinal interneuron development by the Olig-related protein Bhlhb5 and Notch signaling. Development. 2011 Aug;138(15):3199-211. [Abstract] [Article]
Gaber ZB, Novitch BG. All the embryo's a stage, and Olig2 in its time plays many parts. Neuron. 2011 Mar 10;69(5):833-5. [Abstract] [Article]
Huettl RE, Soellner H, Bianchi E, Novitch BG, Huber AB. Npn-1 contributes to  axon-axon interactions that differentially control sensory and motor innervation of the limb. PLoS Biol. 2011 Feb;9(2):e1001020. [Abstract] [Article]
Palmesino E, Rousso DL, Kao TJ, Klar A, Laufer E, Uemura O, Okamoto H, Novitch BG, Kania A. Foxp1 and lhx1 coordinate motor neuron migration with axon trajectory choice by gating Reelin signalling. PLoS Biol. 2010 Aug 10;8(8):e1000446. [Abstract] [Article]
Dessaud E, Ribes V, Balaskas N, Yang LL, Pierani A, Kicheva A, Novitch BG, Briscoe J, Sasai N. Dynamic assignment and maintenance of positional identity in  the ventral neural tube by the morphogen sonic hedgehog. PLoS Biol. 2010 Jun 1;8(6):e1000382. [Abstract] [Article]
Ribes V, Balaskas N, Sasai N, Cruz C, Dessaud E, Cayuso J, Tozer S, Yang LL, Novitch B, Marti E, Briscoe J. Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube. Genes Dev. 2010 Jun 1;24(11):1186-200. [Abstract] [Article]
Novitch BG, Butler SJ. Reducing the mystery of neuronal differentiation. Cell. 2009 Sep 18;138(6):1062-4. [Abstract] [Article]
Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y. Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97. [Abstract] [Article]
Karumbayaram S*, Novitch BG*^, Patterson M, Umbach JA, Richter L, Lindgren A, Conway AE, Clark AT, Goldman SA, Plath K, Wiedau-Pazos M^, Kornblum HI^, Lowry WE^.  Directed differentiation of human-induced pluripotent stem cells generates active motor neurons. Stem Cells. 2009 Apr;27(4):806-11. [Abstract] [Article]
Rousso DL, Gaber ZB, Wellik D, Morrisey EE, Novitch BG. Coordinated actions of the forkhead protein Foxp1 and Hox proteins in the columnar organization of spinal motor neurons. Neuron. 2008 Jul 31;59(2):226-40. [Abstract] [Article] [Nature News and Views] [Nature Neuroscience News and Views]
Briscoe J, Novitch BG. Regulatory pathways linking progenitor patterning, cell fates and neurogenesis in the ventral neural tube. Philos Trans R Soc Lond B Biol Sci. 2008 Jan 12;363(1489):57-70. [Abstract] [Article]
Dessaud E, Yang LL, Hill K, Cox B, Ulloa F, Ribeiro A, Mynett A, Novitch BG,  Briscoe J. Interpretation of the sonic hedgehog morphogen gradient by a temporal  adaptation mechanism. Nature. 2007 Nov 29;450(7170):717-20. [Abstract] [Article]
Mukouyama YS, Deneen B, Lukaszewicz A, Novitch BG, Wichterle H, Jessell TM, Anderson DJ. Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1551-6. [Abstract] [Article]
Marshall CA, Novitch BG, Goldman JE. Olig2 directs astrocyte and oligodendrocyte formation in postnatal subventricular zone cells. J Neurosci. 2005 Aug 10;25(32):7289-98. [Abstract] [Article]
Novitch BG*, Wichterle H*, Jessell TM, Sockanathan S. A requirement for retinoic acid-mediated transcriptional activation in ventral neural patterning and motor neuron specification. Neuron. 2003 Sep 25;40(1):81-95. [Abstract] [Article] [Preview] [Cover Art]
Bylund M, Andersson E, Novitch BG, Muhr J. Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat Neurosci. 2003 Nov;6(11):1162-8. [Abstract][Article] [News and Views]
Qu J, Li X, Novitch BG, Zheng Y, Kohn M, Xie JM, Kozinn S, Bronson R, Beg AA, Minden A. PAK4 kinase is essential for embryonic viability and for proper neuronal development. Mol Cell Biol. 2003 Oct;23(20):7122-33. [Abstract] [Article]
Novitch BG, Chen AI, Jessell TM. Coordinate regulation of motor neuron subtype identity and pan-neuronal properties by the bHLH repressor Olig2. Neuron. 2001 Sep 13;31(5):773-89. [Abstract] [Article] [Neuron Preview] [Cell Preview] [Cover Art]
Novitch BG*, Spicer DB*, Kim PS, Cheung WL, Lassar AB. pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation. Curr Biol. 1999 May 6;9(9):449-59. [Abstract[Article]
Sellers WR, Novitch BG, Miyake S, Heith A, Otterson GA, Kaye FJ, Lassar AB, Kaelin WG Jr. Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth. Genes Dev. 1998 Jan 1;12(1):95-106. [Abstract[Article]
Skapek SX, Rhee J, Kim PS, Novitch BG, Lassar AB. Cyclin-mediated inhibition of muscle gene expression via a mechanism that is independent of pRB hyperphosphorylation. Mol Cell Biol. 1996 Dec;16(12):7043-53. [Abstract[Article]
Novitch BG, Mulligan GJ, Jacks T, Lassar AB. Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle. J Cell Biol. 1996 Oct;135(2):441-56. [Abstract[Article]
Halevy O*, Novitch BG*, Spicer DB, Skapek SX, Rhee J, Hannon GJ, Beach D, Lassar AB. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science. 1995 Feb 17;267(5200):1018-21. [Abstract[Article] [Research News]
Lassar AB, Skapek SX, Novitch B. Regulatory mechanisms that coordinate skeletal muscle differentiation and cell cycle withdrawal. Curr Opin Cell Biol. 1994 Dec;6(6):788-94. [Abstract[Article]
* joint first author publications; ^ joint corresponding author papers